Complement factor H R1210C among Japanese patients with age-related macular degeneration.

doi:10.1007/s10384-015-0394-0

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Article

Complement factor H R1210C among Japanese patients with age-related macular degeneration.

Japanese journal of ophthalmology - 1 Sept 2015

Miyake Masahiro, Saito Masaaki, Yamashiro Kenji, Sekiryu Tetsuju, Yoshimura Nagahisa

Abstract excerpt

PURPOSE: To evaluate the genotype distribution of a rare age-related macular degeneration (AMD)-susceptibility variant, complement factor H (CFH) R1210C, among a large Japanese cohort with AMD. METHODS: One thousand three hundred and sixty-four Japanese patients with neovascular AMD were evaluated. We screened for CFH R1210C (rs121913059) by genotyping with the Taqman method; the mutation was confirmed by Sanger...

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PMID: 26215151
DOI: 10.1007/s10384-015-0394-0

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