Article
CFH polymorphisms in a Northern Spanish population with neovascular and dry forms of age-related macular degeneration.
Acta ophthalmologica - 1 Dec 2015
García Montserrat, Álvarez Lydia, Nogacka Alicja M, González-Iglesias Héctor, Escribano Julio, Fernández-Vega Beatriz, Fernández-Vega Álvaro, Fernández-Vega Luis, Coca-Prados Miguel
Abstract excerpt
PURPOSE: To elucidate the potential role of single-nucleotide polymorphisms (SNPs) in complement factor H (CFH) gene in Northern Spanish patients with age-related macular degeneration (AMD). METHODS: A case-control study of 130 unrelated native Northern Spanish diagnosed with AMD (46 dry, 35 neovascular and 49 mixed) and 96 healthy controls matched by age and ethnicity were enrolled. DNA was isolated from...
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