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Article

Association study of complement factor H, C2, CFB, and C3 and age-related macular degeneration in a Han Chinese population.

Retina (Philadelphia, Pa.) - 1 Sept 2010

Liu Xiaoqi, Zhao Peiquan, Tang Shibo, Lu Fang, Hu Jianbin, Lei Chuntao, Yang Xian, Lin Ying, Ma Shi, Yang Jiyun, Zhang Dingding, Shi Yi, Li Tao, Chen Yiye, Fan Yinchuan, Yang Zhenglin

Abstract excerpt

PURPOSE: Genes in the complement pathway, including complement factor H (CFH), C2/BF, and C3, have been reported to be associated with age-related macular degeneration (AMD). Genetic variants, single-nucleotide polymorphisms (SNPs), in these genes were geno-typed for a case-control association study in a mainland Han Chinese population. METHODS: One hundred and fifty-eight patients with wet AMD, 80 patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20523265
DOI: 10.1097/IAE.0b013e3181cea676

Genes

CFH
CFB
CFHR1
CFHR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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