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Article

Comparison of p16(INK4a) expression with p53 alterations in head and neck cancer by tissue microarray analysis.

The Journal of pathology - 1 Feb 2007

Karsai S, Abel U, Roesch-Ely M, Affolter A, Hofele C, Joos S, Plinkert P K, Bosch F X

Abstract excerpt

We investigated whether there is a relationship between loss of p16(INK4a) protein expression and p53 alterations in head and neck squamous cell carcinomas (HNSCCs). For this purpose, immunohistochemistry was performed on tissue microarrays of 664 tumours; this represents the largest HNSCC cohort studied for molecular biomarkers. Loss of p16(INK4a) protein expression was associated with aberrant p53 expression...

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Source

Identifiers

PMID: 17152048
DOI: 10.1002/path.2100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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