Article
Regulation of myosin II dynamics by phosphorylation and dephosphorylation of its light chain in epithelial cells.
Molecular biology of the cell - 1 Feb 2007
Watanabe Toshiyuki, Hosoya Hiroshi, Yonemura Shigenobu
Abstract excerpt
Nonmuscle myosin II, an actin-based motor protein, plays an essential role in actin cytoskeleton organization and cellular motility. Although phosphorylation of its regulatory light chain (MRLC) is known to be involved in myosin II filament assembly and motor activity in vitro, it remains unclear exactly how MRLC phosphorylation regulates myosin II dynamics in vivo. We established clones of Madin Darby canine...
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