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Article

The essential role of PP1beta in Drosophila is to regulate nonmuscle myosin.

Molecular biology of the cell - 1 Oct 2004

Vereshchagina Natalia, Bennett Daimark, Szöor Balázs, Kirchner Jasmin, Gross Sascha, Vissi Emese, White-Cooper Helen, Alphey Luke

Abstract excerpt

Reversible phosphorylation of myosin regulatory light chain (MRLC) is a key regulatory mechanism controlling myosin activity and thus regulating the actin/myosin cytoskeleton. We show that Drosophila PP1beta, a specific isoform of serine/threonine protein phosphatase 1 (PP1), regulates nonmuscle myosin and that this is the essential role of PP1beta. Loss of PP1beta leads to increased levels of phosphorylated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15269282
DOI: 10.1091/mbc.e04-02-0139
PMCID: PMC519135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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