Article
A Genome-Wide Association Study to Identify Single-Nucleotide Polymorphisms for Acute Kidney Injury.
American journal of respiratory and critical care medicine - 15 Feb 2017
Zhao Bixiao, Lu Qiongshi, Cheng Yuwei, Belcher Justin M, Siew Edward D, Leaf David E, Body Simon C, Fox Amanda A, Waikar Sushrut S, Collard Charles D, Thiessen-Philbrook Heather, Ikizler T Alp, Ware Lorraine B, Edelstein Charles L, Garg Amit X, Choi Murim, Schaub Jennifer A, Zhao Hongyu, Lifton Richard P, Parikh Chirag R
Abstract excerpt
RATIONALE: Acute kidney injury is a common and severe complication of critical illness and cardiac surgery. Despite significant attempts at developing treatments, therapeutic advances to attenuate acute kidney injury and expedite recovery have largely failed. OBJECTIVES: Identifying genetic loci associated with increased risk of acute kidney injury may reveal novel pathways for therapeutic development. METHODS:...
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