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Article

Simulations provide support for the common disease-common variant hypothesis.

Genetics - 1 Feb 2007

Peng Bo, Kimmel Marek

Abstract excerpt

The success of mapping genes involved in complex diseases, using association or linkage disequilibrium methods, depends heavily on the number and frequency of susceptibility alleles of these genes. These methods will be economically and statistically feasible if common diseases are usually influenced by one or a few susceptibility alleles at each locus (common disease-common variant, CDCV, hypothesis), but not so...

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Identifiers

PMID: 17151262
DOI: 10.1534/genetics.106.058164
PMCID: PMC1800600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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