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Article

Ancestral processes for non-neutral models of complex diseases.

Theoretical population biology - 1 Mar 2003

Fearnhead Paul

Abstract excerpt

We consider non-neutral models for unlinked loci, where the fitness of a chromosome or individual is not multiplicative across loci. Such models are suitable for many complex diseases, where there are gene-interactions. We derive a genealogical process for such models, called the complex selection graph (CSG). This coalescent-type process is related to the ancestral selection graph, and is derived from the...

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PMID: 12615495
DOI: 10.1016/s0040-5809(02)00049-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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