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Article

Use of abasic site-containing DNA for electrochemical SNPs detection.

Nucleic acids symposium series (2004) - 1 Jan 2006

Morita Kotaro, Nishizawa Seiichi, Teramae Norio

Abstract excerpt

In combination with an electrode modified with an abasic site-containing DNA duplex, flavins selectively bind to thymine with a useful electrochemical response, and flavins could be successfully utilized for detection of thymine-related mutations. The abasic site provides hydrophobic microenvironments for the hydrogen bond-forming ligands can recognize the specific target base in the DNA duplex, which is detected...

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Identifiers

PMID: 17150832
DOI: 10.1093/nass/nrl045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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