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Article

Sequence-selective 5-methylcytosine oxidation for epigenotyping.

Nucleic acids symposium series (2004) - 1 Jan 2005

Okamoto Akimitsu, Tainaka Kazuki

Abstract excerpt

Methylation of DNA is an epigenetic modification that can play an important role in the control of gene expression in mammalian cells. The development of a simple and convenient method for site-specific discrimination of cytosine methylation is imperative for genomic studies. Here we report a facile method for distinguishing between cytosine and 5-methylcytosine. Osmium tetroxide caused the dihydroxylation of the...

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PMID: 17150625
DOI: 10.1093/nass/49.1.45

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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