Article
Application of 5-Methylcytosine DNA Glycosylase to the Quantitative Analysis of DNA Methylation.
International journal of molecular sciences - 22 Jan 2021
Choi Woo Lee, Mok Young Geun, Huh Jin Hoe
Abstract excerpt
In higher eukaryotes DNA methylation is a prominent epigenetic mark important for chromatin structure and gene expression. Thus, profiling DNA methylation is important for predicting gene expressions associated with specific traits or diseases. DNA methylation is achieved by DNA methyltransferases and can be actively removed by specific enzymes in a replication-independent manner. DEMETER (DME) is a bifunctional...
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