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Mutagenic fingerprint of ozone in human cells.

DNA repair - 30 May 2002

Jorge Soraia A C, Menck Carlos F M, Sies Helmut, Osborne Martin R, Phillips David H, Sarasin Alain, Stary Anne

Abstract excerpt

Ozone is an important factor in urban pollution and represents a major concern for human health. The chemical reactivity of ozone toward biological targets and particularly its genotoxicity supports a possible link between exposure and cancer risk, but no molecular data exist on its mutagenic potential in human cells. Using a shuttle vector, we showed that ozone is indeed a potent mutagen and we characterized the...

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PMID: 12509241
DOI: 10.1016/s1568-7864(02)00011-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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