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Article

Effects of Chronic Rosiglitazone Therapy on Gene Expression in Human Adipose Tissue<i>in Vivo</i>in Patients with Type 2 Diabetes

6 Dec 2006

Abstract excerpt

OBJECTIVE: The aim of this study was to compare effects of therapeutic doses of rosiglitazone and metformin on expression of 50 genes in human adipose tissue in vivo. METHODS: Twenty patients with diet-treated type 2 diabetes (13 women, seven men) were randomized to receive either rosiglitazone (n = 9; 8 mg/d) or metformin (n = 11; 2 g/d) for 16 wk. Subcutaneous adipose tissue biopsies were performed before and...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Identifiers

PMID: 17148569
DOI: 10.1210/jc.2006-1465

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Related research

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Research trail→

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Effects of Chronic Rosiglitazone Therapy on Gene Expression in Human Adipose Tissue<i>in Vivo</i>in Patients with Type 2 DiabetesPMID 17148569Read ↗

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Rosiglitazone treatment of patients with extreme insulin resistance and diabetes mellitus due to insulin receptor mutations has no effects on glucose and lipid metabolism.Semantic proximity Read ↗

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