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Omega-3 fatty acid-rich fish oil supplementation prevents rosiglitazone-induced osteopenia in insulin resistant c57bl/6 mice and in vitro studies.

2020-12-29

Abstract excerpt

Rosiglitazone is an effective insulin-sensitizer, however associated with bone loss mainly due to increased bone resorption and bone marrow adiposity. We investigated the effect of the co-administration of fish oil on rosiglitazone-induced bone loss in C57BL/6 mice and the mechanisms underlying potential preventive effect. Mice fed iso-caloric diet supplemented with fish oil exhibited significantly higher levels o...

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Literature Corpus work
a04b1a5c-7a76-5c36-92c2-319d149ac0e3
DOI
10.21203/rs.3.rs-126494/v1
Open publication

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Omega-3 fatty acid-rich fish oil supplementation prevents rosiglitazone-induced osteopenia in insulin resistant c57bl/6 mice and in vitro studies.DOI 10.21203/rs.3.rs-126494/v1
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