Article
Characterization of lipid metabolism in insulin-sensitive adipocytes differentiated from immortalized human mesenchymal stem cells.
Experimental cell research - 15 Feb 2008
Prawitt Janne, Niemeier Andreas, Kassem Moustapha, Beisiegel Ulrike, Heeren Joerg
Abstract excerpt
There is a great demand for cell models to study human adipocyte function. Here we describe the adipogenic differentiation of a telomerase-immortalized human mesenchymal stem cell line (hMSC-Tert) that maintains numerous features of terminally differentiated adipocytes even after prolonged withdrawal of the peroxisome proliferator activated receptor gamma (PPARgamma) agonist rosiglitazone. Differentiated...
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