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Article

Adipocyte mitochondrial genes and the forkhead factor FOXC2 are decreased in type 2 diabetes patients and normalized in response to rosiglitazone

18 Nov 2011

Abstract excerpt

BACKGROUND: FOXC2 has lately been implicated in diabetes and obesity as well as mitochondrial function and biogenesis and also as a regulator of mtTFA/Tfam. In this study, the expression of FOXC2 and selected genes involved in mitochondrial function and biogenesis in healthy subjects and in a matched cohort with type 2 diabetes patients before and after treatment with rosiglitazone was determined. Quantitative...

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Adipose Tissue and Metabolism
FOXO transcription factor regulation
Regulation of Appetite and Obesity

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22098677
DOI: 10.1186/1758-5996-3-32

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