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Article

Association of MDR1 genotypes with susceptibility to colorectal cancer in older non-smokers.

European journal of clinical pharmacology - 1 Jan 2007

Osswald Elena, Johne Andreas, Laschinski Gabriele, Arjomand-Nahad Farhad, Malzahn Uwe, Kirchheiner Julia, Gerloff Thomas, Meisel Christian, Mrozikiewicz Przemyslaw M, Chernov Jury, Roots Ivar, Köpke Karla

Abstract excerpt

OBJECTIVE: The multidrug resistance gene 1 (MDR1) seems to play a role in the carcinogenesis of colorectal tumors. The importance of MDR1 SNPs 2677G > T/A in exon 21 and 3435C > T in exon 26 for cancer susceptibility, however, has not yet been clearly defined. METHODS: Two hundred and eighty-five colorectal cancer patients and 275 controls from five hospitals in the European part of Russia were genotyped for the...

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PMID: 17146660
DOI: 10.1007/s00228-006-0225-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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