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Article

Effects of genetic polymorphisms of MDR1, FMO3 and CYP1A2 on susceptibility to colorectal cancer in Koreans.

Cancer science - 1 Aug 2006

Bae Sun-Young, Choi Sun-Keun, Kim Kyung-Rae, Park Chang-Shin, Lee Sung-Keun, Roh Hyung-Keun, Shin Dong-Woon, Pie Jae-Eun, Woo Ze-Hong, Kang Ju-Hee

Abstract excerpt

The aim of the present study was to evaluate the effects on the susceptibility to colorectal cancer (CRC) of genetic polymorphisms in P-glycoprotein (PGP) and the metabolic enzymes cytochrome P450 1A2 (CYP1A2) and flavin-containing monooxygenase 3 (FMO3). We analyzed five single-nucleotide polymorphisms (SNP) in 93 cancer-free volunteers and 111 patients with CRC: one common genetic variant of the PGP-encoding...

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Identifiers

PMID: 16800822
DOI: 10.1111/j.1349-7006.2006.00241.x
PMCID: PMC11160064

Genes

FMO3
PGP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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