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Article

Epigenetic silencing of novel tumor suppressors in malignant melanoma.

Cancer research - 1 Dec 2006

Muthusamy Viswanathan, Duraisamy Sekhar, Bradbury C Matthew, Hobbs Cara, Curley David P, Nelson Betsy, Bosenberg Marcus

Abstract excerpt

Malignant melanoma is a common and frequently lethal disease. Current therapeutic interventions have little effect on survival, emphasizing the need for a better understanding of the genetic, epigenetic, and phenotypic changes in melanoma formation and progression. We identified 17 genes that were not previously known to be silenced by methylation in melanoma using a microarray-based screen following treatment of...

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Identifiers

PMID: 17145863
DOI: 10.1158/0008-5472.CAN-06-1274

Genes

HOXB13
LXN
QPCT
SYK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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