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Article

Identification of metastasis-related genes in a mouse model using a library of randomized ribozymes.

The Journal of biological chemistry - 10 Sept 2004

Suyama Eigo, Wadhwa Renu, Kaur Kamaljit, Miyagishi Makoto, Kaul Sunil C, Kawasaki Hiroaki, Taira Kazunari

Abstract excerpt

Libraries of randomized ribozymes have considerable potential as tools for the identification of functional genes critically involved in a biological phenotype of interest in vitro. We have used a ribozyme library in an in vivo mouse model to identify genes related to metastasis. We injected weakly metastatic melanoma cells that had been treated with the library intravenously into mice. We then isolated ribozymes...

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PMID: 15247279
DOI: 10.1074/jbc.C400313200

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STIM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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