Cardiac metabolism and mechanics are altered by genetic loss of lipoprotein triglyceride lipolysis.

Abstract excerpt

INTRODUCTION: Most circulating fatty acids are contained in lipoprotein triglycerides. For the heart to acquire these lipids, they must be broken down into free fatty acids via the enzyme lipoprotein lipase (LpL). Although it has long been known that hearts primarily use esterified fatty acids as fuel, different sources of fatty acids were thought to be interchangeable. MATERIALS AND METHODS: By creating mice...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cardiomyopathy, Dilated
• Share to Energy Metabolism
• Share to Fatty Acids