Article
The C allele of the GNB3 C825T polymorphism of the G protein beta3-subunit is associated with an increased risk for the development of oncocytic thyroid tumours.
The Journal of pathology - 1 Jan 2007
Sheu S-Y, Handke S, Bröcker-Preuss M, Görges R, Frey U H, Ensinger C, Ofner D, Farid N R, Siffert W, Schmid K W
Abstract excerpt
Carriers of the C allele of the common C825T polymorphism in the GNB3 gene of the G protein have been associated with the development of follicular thyroid adenomas. Since the C allele of this polymorphism is related to a lower signalling capacity, it was speculated whether the C825T polymorphism...
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