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Article

Risk of non-medullary thyroid cancer influenced by polymorphic variation in the thyroglobulin gene.

Carcinogenesis - 1 Mar 2004

Matakidou Athena, Hamel Nancy, Popat Sanjay, Henderson Kiersten, Kantemiroff Tania, Harmer Clive, Clarke Susan E M, Houlston Richard S, Foulkes William D

Abstract excerpt

Benign thyroid disorders are strong risk factors for non-medullary thyroid cancer (NMTC). Germline variation in Tg (thyroglobulin) and TSHR (thyroid stimulating hormone receptor) confers an increased risk of benign thyroid disorders. To explore the hypothesis that polymorphic variation in these genes affects the risk of NMTC we compared the frequency of TgQ2511R, TSHR-P52T and TSHR-D727E genotypes in two series...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14633662
DOI: 10.1093/carcin/bgh027

Genes

TSHR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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