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Article

The potential role of the sodium iodide symporter gene polymorphism in the development of differentiated thyroid cancer.

Gene - 10 Nov 2015

Al-Rasheed Maha M, Alzahrani Ali S, Macadam Angela, Overall Andrew, Gard Paul, Dzimiri Nduna

Abstract excerpt

The sodium iodide symporter (NIS) (solute carrier family 5; SLC5A), mediates the active transport of iodine anion (I(-)) into thyroid follicular cells to facilitate thyroid hormone biosynthesis. Considering its fundamental role in thyroid function, our objective in this study is to explore its potential involvement in the pathogenesis of differentiated thyroid cancer (DTC). Following a preliminary sequencing of...

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Identifiers

PMID: 26160439
DOI: 10.1016/j.gene.2015.07.009

Genes

AGT
CGA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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