Article
TNFa-e microsatellite, HLA-DRB1 and -DQB1 alleles and haplotypes in Brazilian patients presenting recently diagnosed type 1 diabetes mellitus.
Annals of the New York Academy of Sciences - 1 Oct 2006
Rassi Diane M, Wastowski Isabela J, Simões Renata T, Rodrigues Sandra, Deghaide Neife N H S, Mendes-Junior Celso T, Simões Aguinaldo L, Soares C P, Passos Geraldo A S, Donadi Eduardo A
Abstract excerpt
TNF microsatellite and HLA class II polymorphisms were studied in 28 recently diagnosed Brazilian patients presenting type 1 diabetes mellitus (T1DM) and in 120 healthy controls. TNFa-e and HLA-DRB1/DQB1 alleles were identified using sets of sequence-specific primers. Compared to controls, the DRB1*03 and DQB1*02 allele groups, TNFa1 allele, and the TNFa4-b5-c1-d4-e3 and TNFa10-b5-c1-d4-e3 haplotypes were...
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