Article
Is the association between TNF-alpha-308 A allele and DMT1 independent of HLA-DRB1, DQB1 alleles?
Mediators of inflammation - 1 Jan 2006
Deja Grazyna, Jarosz-Chobot Przemysława, Polańska Joanna, Siekiera Urszula, Małecka-Tendera Ewa
Abstract excerpt
The aim of the study was to assess chosen factors of genetic susceptibility to DMT1: DRB1, DQB1, and TNF-alpha polymorphisms-308 (G/A) in children with DMT1 and their up-to-now healthy siblings. Then we tested whether the association between TNF-alpha genes and DMT1 is independent of HLA. 87 diabetic children, their 78 siblings, and 85 persons from healthy control group were followed up. The highest risk of DMT1...
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