Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of single-nucleotide polymorphisms in tumour necrosis factor and human leukocyte antigens genes with type 1 diabetes.

International journal of immunogenetics - 1 Aug 2021

Osman Awad Elsid, Brema Imad, AlQurashi Alaa, Al-Jurayyan Abdullah, Bradley Benjamin, Hamza Muaawia Ahmed

Abstract excerpt

Type 1 diabetes (T1D) is an autoimmune disease characterized by progressive destruction of insulin-producing pancreatic beta cells. This multifactorial disease has a strong genetic component associated with the human leukocyte antigens (HLA) and non-HLA regions. In this study, we compared frequencies of HLA-DRB1 alleles and single-nucleotide polymorphisms (SNPs) associated the genes coding for: toll-like...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 1
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA Antigens

Share to Interleukin-1

Share to Interleukin-12

Share to Interleukin-2

Share to Toll-Like Receptors

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 34018329
DOI: 10.1111/iji.12535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of single-nucleotide polymorphisms in tumour necrosis factor and human leukocyte antigens genes with type 1 diabetes.PMID 34018329Read ↗

Association of the Immunity Genes with Type 1 Diabetes Mellitus.Semantic proximity Read ↗

Independent association of tumor necrosis factor polymorphism with type 1 diabetes susceptibility.Semantic proximity Read ↗

Single nucleotide polymorphism rs 2070874 at Interleukin-4 is associated with increased risk of type 1 diabetes mellitus independently of human leukocyte antigens.Semantic proximity Read ↗

Identification of specific tumor necrosis factor-α-susceptible and -protective haplotypes associated with the risk of type 1 diabetes.Semantic proximity Read ↗

Genetic susceptibility to type 1 diabetes mellitus in humans.Semantic proximity Read ↗

Tumor necrosis factor-associated susceptibility to type 1 diabetes is caused by linkage disequilibrium with HLA-DR3 haplotypes.Semantic proximity Read ↗

Linkage disequilibrium with HLA-DRB1-DQB1 haplotypes explains the association of TNF-308G>A variant with type 1 diabetes in a Brazilian cohort.Semantic proximity Read ↗

Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases.Semantic proximity Read ↗

Immunogenetics of type 1 diabetes: A comprehensive review.Semantic proximity Read ↗

Association of TNF-α, CTLA4, and PTPN22 polymorphisms with type 1 diabetes and other autoimmune diseases in Brazil.Semantic proximity Read ↗

Immunogenetics of type 1 diabetes.Semantic proximity Read ↗

Association of 32 type 1 diabetes risk loci in Pakistani patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.