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Article

Specificity protein 1 transcription factor regulates human ARTS promoter activity through multiple binding sites.

PloS one - 1 Jan 2015

Xu Feifan, Sun Wei, Li Pan, Chen Jinling, Zhu Dandan, Sun Xiaolei, Wang Jianxin, Feng Jinrong, Song Ke, Duan Yinong

Abstract excerpt

Apoptosis-related protein in the TGF-β signaling pathway (ARTS) is an unusual mitochondrial Septin-like protein which functions as a tumor suppressor. There are various splice variants derived from the human Septin4 gene, one of which is ARTS, also known as Septin4_i2. Unlike other Septin4 members, ARTS can induce apoptosis in many cells, however, the underlying molecular mechanism for the transcriptional...

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Identifiers

PMID: 25790304
DOI: 10.1371/journal.pone.0120072
PMCID: PMC4366172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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