Article
Novel mutations found in mitochondrial diabetes in Chinese Han population.
Diabetes research and clinical practice - 1 Jun 2007
Liu Song-Mei, Zhou Xin, Zheng Fang, Li Xia, Liu Fang, Zhang Hong-Mei, Xie Yan
Abstract excerpt
Mitochondria provide cells with most of the energy in the form of ATP. Mutations in mitochondrial DNA (mtDNA) are associated with type 2 diabetes mellitus (T2DM) because ATP plays a critical role in the production and the release of insulin. To systematically determine mutant loci and to investigate their association with T2DM in Chinese Han population, 17 commonly reported mutant loci were screened in 236 cases...
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