Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel mitochondrial 16S rRNA mutation, 3200T-->C, associated with adult-onset type 2 diabetes.

Chinese medical journal - 1 May 2002

Yang Tao, Lam Ching-Wan, Tsang Man-Wo, Tong Sui-Fan, Kam Grace Y W, Chan Lisa Y S, Poon Priscilla M K, Wu Xiangqian, Pang Chi-Pu

Abstract excerpt

OBJECTIVE: To investigate the role of a potential diabetes-related mitochondrial region, which includes two previously reported mutations, 3243A-->G and 3316G-->A, in Chinese patients with adult-onset type 2 diabetes. METHODS: A total of 277 patients and 241 normal subjects were recruited for the study. Mitochondrial nt 3116 - 3353, which spans the 16S rRNA, tRNA(leu(UUR)) and the NADH dehydrogenase 1 gene, were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Mitochondrial

Share to Models, Molecular

Share to Nucleic Acid Conformation

Share to Point Mutation

Share to Polymorphism, Restriction Fragment Length

Share to RNA, Ribosomal, 16S

Source

Identifiers

PMID: 12133550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel mitochondrial 16S rRNA mutation, 3200T-->C, associated with adult-onset type 2 diabetes.PMID 12133550Read ↗

Novel mutations found in mitochondrial diabetes in Chinese Han population.Semantic proximity Read ↗

Maternally inherited diabetes is associated with a homoplasmic T10003C mutation in the mitochondrial tRNA(Gly) gene.Semantic proximity Read ↗

[Mutations of mitochondrial 12S rRNA gene in type 2 diabetes].Semantic proximity Read ↗

Mitochondrial Diabetes Is Associated with the ND4 G11696A Mutation.Semantic proximity Read ↗

Mutation at position 5628 in the mitochondrial tRNAAla gene in a Chinese pedigree with maternally diabetes mellitusSemantic proximity Read ↗

[Association of mitochondrial DNA variation with type 2 diabetes mellitus].Semantic proximity Read ↗

Mitochondrial DNA mutations in diabetes mellitus patients in Chinese Han population.Semantic proximity Read ↗

The tRNA(Gly) T10003C mutation in mitochondrial haplogroup M11b in a Chinese family with diabetes decreases the steady-state level of tRNA(Gly), increases aberrant reactive oxygen species production, and reduces mitochondrial membrane potential.Semantic proximity Read ↗

Mitochondrial gene variation in type 2 diabetes mellitus: detection of a novel mutation associated with maternally inherited diabetes in a Chinese family.Semantic proximity Read ↗

Role of mitochondrial DNA in diabetes Mellitus Type I and Type IISemantic proximity Read ↗

Mitochondrial gene mutations in the tRNA(Leu(UUR)) region and diabetes: prevalence and clinical phenotypes in Japan.Semantic proximity Read ↗

Mitochondrial DNA Mutations Associated with Type 2 Diabetes Mellitus in Chinese Uyghur Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.