Article
Mitochondrial Diabetes Is Associated with the ND4 G11696A Mutation.
Biomolecules - 30 May 2023
Ding Yu, Zhang Shunrong, Guo Qinxian, Leng Jianhang
Abstract excerpt
Type 2 diabetes mellitus (T2DM) is a common endocrine disorder which remains a large challenge for clinicians. Previous studies have suggested that mitochondrial dysfunction plays an active role in T2DM progression, but a detailed mechanism is still elusive. In the current study, two Han Chinese families with maternally inherited T2DM were evaluated using clinical, genetic, molecular, and biochemical analyses....
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