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Article

Recurrent gene amplification and soft selective sweeps during evolution of multidrug resistance in malaria parasites.

Molecular biology and evolution - 1 Feb 2007

Nair Shalini, Nash Denae, Sudimack Daniel, Jaidee Anchalee, Barends Marion, Uhlemann Anne-Catrin, Krishna Sanjeev, Nosten François, Anderson Tim J C

Abstract excerpt

When selection is strong and beneficial alleles have a single origin, local reductions in genetic diversity are expected. However, when beneficial alleles have multiple origins or were segregating in the population prior to a change in selection regime, the impact on genetic diversity may be less...

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Identifiers

PMID: 17124182
DOI: 10.1093/molbev/msl185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17124182-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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