Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of Smooth Muscle Cell Proliferation by β-Catenin/T-Cell Factor Signaling Involves Modulation of Cyclin D1 and p21 Expression

23 Nov 2006

Abstract excerpt

We previously observed that stimulation of vascular smooth muscle cell (VSMC) proliferation with growth factors is associated with dismantling of cadherin junctions and nuclear translocation of beta-catenin. In this study we demonstrate directly that growth factors stimulate beta-catenin/T-cell factor (TCF) signaling in primary VSMCs. To determine whether beta-catenin/TCF signaling regulates VSMC proliferation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Cancer-related Molecular Pathways
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17122440
DOI: 10.1161/01.res.0000253533.65446.33

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of Smooth Muscle Cell Proliferation by β-Catenin/T-Cell Factor Signaling Involves Modulation of Cyclin D1 and p21 ExpressionPMID 17122440Read ↗

T-cadherin upregulation correlates with cell-cycle progression and promotes proliferation of vascular cellsSemantic proximity Read ↗

Dismantling of cadherin-mediated cell-cell contacts modulates smooth muscle cell proliferation.Semantic proximity Read ↗

Contribution of the helix-loop-helix factor Id2 to regulation of vascular smooth muscle cell proliferation.Semantic proximity Read ↗

A novel mechanism of transcriptional repression of p27kip1 through Notch/HRT2 signaling in vascular smooth muscle cells.Semantic proximity Read ↗

Vascular smooth muscle cell proliferation and its therapeutic modulation in hypertension.Semantic proximity Read ↗

Rat vascular smooth muscle cells immortalized with SV40 large T antigen possess defined smooth muscle cell characteristics including growth inhibition by heparin.Semantic proximity Read ↗

A calmodulin-binding site on cyclin E mediates Ca2+-sensitive G1/s transitions in vascular smooth muscle cells.Semantic proximity Read ↗

Overexpression of p21Waf1 induces apoptosis in immortalized human vascular smooth muscle cells.Semantic proximity Read ↗

p53, p21(WAF1/CIP1), and MDM2 involvement in the proliferation and apoptosis in an in vitro model of conditionally immortalized human vascular smooth muscle cells.Semantic proximity Read ↗

p53, p21(WAF1/CIP1), and MDM2 involvement in proliferation and apoptosis in an in vitro model of conditionally immortalized human vascular smooth muscle cells.Semantic proximity Read ↗

Retinoids inhibit proliferation of human coronary smooth muscle cells by modulating cell cycle regulators.Semantic proximity Read ↗

Cell adhesion molecule T-cadherin regulates vascular cell adhesion, phenotype and motility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.