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Article

Retinoids inhibit proliferation of human coronary smooth muscle cells by modulating cell cycle regulators.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2001

Wakino S, Kintscher U, Kim S, Jackson S, Yin F, Nagpal S, Chandraratna R A, Hsueh W A, Law R E

Abstract excerpt

Retinoids inhibit rat vascular smooth muscle cell (VSMC) proliferation in vitro and intimal hyperplasia in vivo. We examined the mechanism of the antiproliferative effect of retinoids on human coronary artery smooth muscle cells (human CASMCs). The RAR ligands all-trans-retinoic acid (atRA) and ethyl-p-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-l-propenyl]-benzoic acid (TTNPB); a pan-RXR/RAR...

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Identifiers

PMID: 11348869
DOI: 10.1161/01.atv.21.5.746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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