Article
Yersinia protein kinase YopO is activated by a novel G-actin binding process.
The Journal of biological chemistry - 26 Jan 2007
Trasak Claudia, Zenner Gerhardt, Vogel Annette, Yüksekdag Gülnihal, Rost René, Haase Ilka, Fischer Markus, Israel Lars, Imhof Axel, Linder Stefan, Schleicher Michael, Aepfelbacher Martin
Abstract excerpt
Pathogenic bacteria of the genus Yersinia employ a type III secretion system to inject effector proteins (Yops) into host cells. The Yops down-regulate host cell functions through unique biochemical activities. YopO, a serine/threonine kinase required for Yersinia virulence, is activated by host...
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