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Article

Effects of functional genetic polymorphisms in the CYP19A1 gene on prostate cancer risk and survival.

International journal of cancer - 1 Jan 2015

Kanda Sohei, Tsuchiya Norihiko, Narita Shintaro, Inoue Takamitsu, Huang Mingguo, Chiba Syuji, Akihama Susumu, Saito Mitsuru, Numakura Kazuyuki, Tsuruta Hiroshi, Satoh Shigeru, Saito Seiichi, Ohyama Chikara, Arai Yoichi, Ogawa Osamu, Habuchi Tomonori

Abstract excerpt

CYP19 catalyzes the conversion of androgens to estrogens and is a critical enzyme affecting the sex hormone milieu. In this study, we investigated the functions of CYP19A1 polymorphisms and their associations with prostate cancer risk and clinical outcome. This case-control study evaluated the effects of three single nucleotide polymorphisms (SNPs) in CYP19A1 on the risk of prostate cancer in 330 prostate cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24803183
DOI: 10.1002/ijc.28952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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