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TP53 alterations and colorectal cancer predisposition in south Indian population: a case-control study.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2014

Singamsetty Gopi Krishna, Malempati Sravanthi, Bhogadhi Srichandana, Kondreddy Ravinder, Govatati Suresh, Tangudu Naveen Kumar, Govatati Sowdamani, kuraganti Anil Kumar, Bhanoori Manjula, Kassetty Kondaiah

Abstract excerpt

The objective of the present study was to investigate the association between TP53 gene single nucleotide polymorphisms (SNPs) and colorectal cancer (CRC) predisposition in south Indian population and to evaluate the role of TP53 expression in the pathophysiology of CRC. A genetic association study was conducted in 103 CRC cases and 107 controls of south Indian origin. We genotyped ten selected TP53 SNPs by...

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PMID: 24158910
DOI: 10.1007/s13277-013-1305-y

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