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Article

BMP type I receptor ALK2 is essential for proper patterning at late gastrulation during mouse embryogenesis.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Feb 2007

Komatsu Yoshihiro, Scott Gregory, Nagy Andre, Kaartinen Vesa, Mishina Yuji

Abstract excerpt

Bone morphogenetic proteins (BMPs) have multiple functions during vertebrate development. Previously, it was shown that BMP type I receptor ALK2 (also known as ACVRI, ActRI, or ActRIA) was important for normal mouse gastrulation by deleting exon 4 or exon 5 of Alk2. Recently, flanking exon 7 by loxP sites generated a conditional allele for Alk2. To assess whether the deletion of exon 7 causes functional null of...

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Identifiers

PMID: 17117439
DOI: 10.1002/dvdy.21021
PMCID: PMC1780255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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