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Article

HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer.

British journal of cancer - 18 Dec 2006

Benusiglio P R, Pharoah P D, Smith P L, Lesueur F, Conroy D, Luben R N, Dew G, Jordan C, Dunning A, Easton D F, Ponder B A J

Abstract excerpt

ERBB2 is frequently amplified in breast tumours as part of a wide region of amplification on chromosome 17q21. This amplicon contains many candidate genes for breast cancer susceptibility. We used a genetic association study design to determine if common genetic variation (frequency>or=5%) in a 400-kb region surrounding ERBB2 and containing the PPARBP, CRK7, NEUROD2, PPP1R1B, STARD3, TCAP, PNMT, CAB2, ERBB2,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Chromosomes, Human, Pair 17

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Share to Receptor, ErbB-2

Source

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Identifiers

PMID: 17117180
DOI: 10.1038/sj.bjc.6603473
PMCID: PMC2360759

Genes

ERBB2
GRB7
NEUROD2
PNMT
STARD3
TCAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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