Article
Fine scale mapping of the breast cancer 16q12 locus.
Human molecular genetics - 15 Jun 2010
Udler Miriam S, Ahmed Shahana, Healey Catherine S, Meyer Kerstin, Struewing Jeffrey, Maranian Melanie, Kwon Erika M, Zhang Jinghui, Tyrer Jonathan, Karlins Eric, Platte Radka, Kalmyrzaev Bolot, Dicks Ed, Field Helen, Maia Ana-Teresa, Prathalingam Radhika, Teschendorff Andrew, McArthur Stewart, Doody David R, Luben Robert, Caldas Carlos, Bernstein Leslie, Kolonel Laurence K, Henderson Brian E, Wu Anna H, Le Marchand Loic, Ursin Giske, Press Michael F, Lindblom Annika, Margolin Sara, Shen Chen-Yang, Yang Show-Lin, Hsiung Chia-Ni, Kang Daehee, Yoo Keun-Young, Noh Dong-Young, Ahn Sei-Hyun, Malone Kathleen E, Haiman Christopher A, Pharoah Paul D, Ponder Bruce A J, Ostrander Elaine A, Easton Douglas F, Dunning Alison M
Abstract excerpt
Recent genome-wide association studies have identified a breast cancer susceptibility locus on 16q12 with an unknown biological basis. We used a set of single nucleotide polymorphism (SNP) markers to generate a fine-scale map and narrowed the region of association to a 133 kb DNA segment containing the largely uncharacterized hypothetical gene LOC643714, a short intergenic region and the 5' end of TOX3....
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