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Article

Common ERBB2 polymorphisms and risk of breast cancer in a white British population: a case-control study.

Breast cancer research : BCR - 1 Jan 2005

Benusiglio Patrick R, Lesueur Fabienne, Luccarini Craig, Conroy Donald M, Shah Mitul, Easton Douglas F, Day Nick E, Dunning Alison M, Pharoah Paul D, Ponder Bruce Aj

Abstract excerpt

INTRODUCTION: About two-thirds of the excess familial risk associated with breast cancer is still unaccounted for and may be explained by multiple weakly predisposing alleles. A gene thought to be involved in low-level predisposition to the disease is ERBB2 (HER2). This gene is involved in cell division, differentiation, and apoptosis and is frequently amplified in breast tumours. Its amplification correlates...

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Source

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Identifiers

PMID: 15743501
DOI: 10.1186/bcr982
PMCID: PMC1064135

Genes

ERBB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Common ERBB2 polymorphisms and risk of breast cancer in a white British population: a case-control study.PMID 15743501Read ↗

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HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer.Semantic proximity Read ↗

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