Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

No effect of polymorphisms in the non-duplicated region of the CHRNA7 gene on sensory gating P50 ratios in patients with schizophrenia and bipolar disorder.

Psychiatry research - 28 Feb 2013

Cabranes José Antonio, Ancín Inés, Santos José Luis, Sánchez-Morla Eva, García-Jiménez María Ángeles, López-Ibor Juan José, Barabash Ana

Abstract excerpt

Previous research has reported that bipolar disorder and schizophrenic patients evidence sensory gating deficits. The use of intermediate phenotypes may facilitate genetic studies. Four single nucleotide polymorphisms (SNPs) located on the non-duplicated region of the alpha-7 nicotinic receptor gene (CHRNA7) were genotyped in 95 healthy subjects, 127 bipolar disorder and 153 schizophrenic patients. We evaluated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha7 Nicotinic Acetylcholine Receptor
Share to Bipolar Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CHRNA7 gene

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Receptors, Nicotinic

Share to Schizophrenia

Share to Sensory Gating

Source

Identifiers

PMID: 22981153
DOI: 10.1016/j.psychres.2012.08.015

Genes

CHRNA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

No effect of polymorphisms in the non-duplicated region of the CHRNA7 gene on sensory gating P50 ratios in patients with schizophrenia and bipolar disorder.PMID 22981153Read ↗

The -2 bp deletion in exon 6 of the 'alpha 7-like' nicotinic receptor subunit gene is a risk factor for the P50 sensory gating deficit.Semantic proximity Read ↗

The promoter -194 C polymorphism of the nicotinic alpha 7 receptor gene has a protective effect against the P50 sensory gating deficit.Semantic proximity Read ↗

Sensory gating and alpha-7 nicotinic receptor gene allelic variants in schizoaffective disorder, bipolar type.Semantic proximity Read ↗

Association Study of CHRNA7 Promoter Variants with Sensory and Sensorimotor Gating in Schizophrenia Patients and Healthy Controls: A Danish Case-Control Study.Semantic proximity Read ↗

Identification of molecular variants at the promoter region of the human alpha 7 neuronal nicotinic acetylcholine receptor subunit gene but lack of association with schizophrenia.Semantic proximity Read ↗

Association study of polymorphisms in the alpha 7 nicotinic acetylcholine receptor subunit and catechol-o-methyl transferase genes with sensory gating in first-episode schizophrenia.Semantic proximity Read ↗

Linkage disequilibrium analysis of the CHRNA7 gene and its partially duplicated region in schizophrenia.Semantic proximity Read ↗

Association of the 5'-upstream regulatory region of the alpha7 nicotinic acetylcholine receptor subunit gene (CHRNA7) with schizophrenia.Semantic proximity Read ↗

Evidence for association of the non-duplicated region of CHRNA7 gene with bipolar disorder but not with Schizophrenia.Semantic proximity Read ↗

Association of promoter variants in the alpha7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia.Semantic proximity Read ↗

Association of Common Polymorphisms in the Nicotinic Acetylcholine Receptor Alpha4 Subunit Gene with an Electrophysiological Endophenotype in a Large Population-Based Sample.Semantic proximity Read ↗

Evidence of association between smoking and alpha7 nicotinic receptor subunit gene in schizophrenia patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.