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Article

Host cytokine genotype is related to adverse prognosis and systemic inflammation in gastro-oesophageal cancer.

Annals of surgical oncology - 1 Feb 2007

Deans Chris, Rose-Zerilli Matthew, Wigmore Stephen, Ross James, Howell Martin, Jackson Alan, Grimble Robert, Fearon Kenneth

Abstract excerpt

BACKGROUND: Systemic inflammation has been linked with reduced survival in cancer, however, the role of the host cytokine genotype versus tumour phenotype in the generation of this response is not clearly established. This study examined the relationship between cytokine polymorphisms (IL-1beta 511, IL-6 174, IL-10 1082, TNFalpha 308 and LTalpha +252) and serum cytokine concentrations, serum CRP concentration and...

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PMID: 17103073
DOI: 10.1245/s10434-006-9122-9

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CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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