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Article

Genetic polymorphisms and the risk of infection following esophagectomy. positive association with TNF-alpha gene -308 genotype.

Annals of surgery - 1 Jul 2007

Azim Kaukab, McManus Ross, Brophy Karen, Ryan Aoife, Kelleher Dermot, Reynolds John V

Abstract excerpt

OBJECTIVE: To examine the association of single nucleotide polymorphisms (SNPs) in inflammation-related genes in the development of infections following esophagectomy. SUMMARY BACKGROUND DATA: Genetic polymorphisms for immunoregulatory cytokines may explain individual variation in response to trauma. Esophagectomy is associated with a high risk of postoperative infection and sepsis, and this study explored a...

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Identifiers

PMID: 17592300
DOI: 10.1097/01.sla.0000259389.09161.49
PMCID: PMC1899211

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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