Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer cachexia is associated with the IL10 -1082 gene promoter polymorphism in patients with gastroesophageal malignancy.

The American journal of clinical nutrition - 1 Apr 2009

Deans D A Chris, Tan Benjamin H L, Ross James A, Rose-Zerilli Matthew, Wigmore Stephen J, Howell W Martin, Grimble Robert F, Fearon Kenneth C H

Abstract excerpt

BACKGROUND: The genetic predisposition of the host to local or systemic inflammation may contribute to the effect of cancer cachexia. OBJECTIVE: We investigated the relation between cytokine polymorphisms (IL1B -511, IL6 -174, IL10 -1082, TNFA -308, and LTA +252) and markers of nutritional status among patients with gastroesophageal cancer to determine whether any such association was reflected by cytokine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to C-Reactive Protein
Share to Cachexia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

Share to Interleukin-10

Share to Multivariate Analysis

Share to Nutrition Assessment

Share to Nutritional Status

Share to Stomach Neoplasms

Source

Identifiers

PMID: 19244371
DOI: 10.3945/ajcn.2008.27025

Genes

LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer cachexia is associated with the IL10 -1082 gene promoter polymorphism in patients with gastroesophageal malignancy.PMID 19244371Read ↗

Cytokine gene polymorphisms and susceptibility to cachexia.Semantic proximity Read ↗

Host cytokine genotype is related to adverse prognosis and systemic inflammation in gastro-oesophageal cancer.Semantic proximity Read ↗

Interleukin-10 gene polymorphisms influence susceptibility to cachexia in patients with low-third gastric cancer in a Chinese population.Semantic proximity Read ↗

The -1082A>G polymorphism in promoter region of interleukin-10 and risk of digestive cancer: a meta-analysis.Semantic proximity Read ↗

Association of interleukin-10 gene polymorphism with cachexia in Chinese patients with gastric cancer.Semantic proximity Read ↗

Interleukin-10 gene promoter polymorphisms and risk of gastric cancer in a Chinese population: single nucleotide and haplotype analyses.Semantic proximity Read ↗

Cytokine gene polymorphisms and the risk of adenocarcinoma of the stomach in the European prospective investigation into cancer and nutrition (EPIC-EURGAST).Semantic proximity Read ↗

[Association of interleukin-10 gene polymorphism with cachexia in patients with gastric cancer].Semantic proximity Read ↗

Relationship between TNF-α -1031T/C gene polymorphism, plasma level of TNF-α, and risk of cachexia in head and neck cancer patients.Semantic proximity Read ↗

Association of IL-6 gene polymorphisms with cachexia susceptibility and survival time of patients with pancreatic cancer.Semantic proximity Read ↗

Genetic modulation of the interleukin 6 (IL-6) system in patients with advanced gastric cancer: a background for an alternative target therapy.Semantic proximity Read ↗

Association of IL-1beta gene polymorphism with cachexia from locally advanced gastric cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.