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Article

Prion protein gene M129V polymorphism and variability in age at migraine onset.

Headache - 1 Mar 2013

Palmirotta Raffaele, Ludovici Giorgia, Egeo Gabriella, Ialongo Cristiano, Aurilia Cinzia, Fofi Luisa, De Marchis Maria Laura, Della-Morte David, Barbanti Piero, Guadagni Fiorella

Abstract excerpt

Prion protein, a sialoglycoprotein with neuroprotective properties on oxidative stress damage, has been related with the mechanisms leading to migraine. In the present case-control study, we investigated the correlation between the common methionine/valine polymorphism at codon 129 within the prion protein gene (PRNP) and migraine. Genotyping of PRNP V129M variant was performed in 384 migraine patients and 185...

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Identifiers

PMID: 23405858
DOI: 10.1111/head.12043

Genes

PRNP

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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