Effect of genetic variants of CCR2 and CCL2 on the natural history of HIV-1 infection: CCL2-2518GG is overrepresented in a cohort of Spanish HIV-1-infected subjects.

doi:10.1097/QAI.0b013e31802b3147

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Article

Effect of genetic variants of CCR2 and CCL2 on the natural history of HIV-1 infection: CCL2-2518GG is overrepresented in a cohort of Spanish HIV-1-infected subjects.

Journal of acquired immune deficiency syndromes (1999) - 1 Feb 2007

Viladés Consuelo, Broch Montserrat, Plana Montserrat, Domingo Pere, Alonso-Villaverde Carlos, Pedrol Enric, Knobel Hernando, Dalmau David, Peraire Joaquim, Gutiérrez Cristina, López Anna, Sambeat Maria Antònia, Olona Montserrat, Garcia Felipe, Richart Cristóbal, Gatell Josep Maria, Vidal Francesc

Abstract excerpt

BACKGROUND AND OBJECTIVES: Polymorphisms in the genes that encode for the CCR2 chemokine receptor and its natural ligand CCL2 have been shown to influence the natural history of HIV-1 infection, although data are inconsistent. Our aim was to determine whether functionally active CCR2 and CCL2 genetic variants influence the risk of infection and disease progression in a cohort of white Spaniards. PATIENTS AND...

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Identifiers

PMID: 17091019
DOI: 10.1097/QAI.0b013e31802b3147

Genes

CCL2
CCR2
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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