Article
Host-pathogen interactions in the development of metabolic disturbances and atherosclerosis in HIV infection: the role of CCL2 genetic variants.
Cytokine - 1 Sept 2010
Alonso-Villaverde Carlos, Aragonès Gerard, Beltrán-Debón Raúl, Fernández-Sender Laura, Rull Anna, Rodríguez-Sanabria Fernando, Marsillach Judit, Pardo-Reche Pedro, Camps Jordi, Joven Jorge
Abstract excerpt
BACKGROUND: Circulating CCL2 concentration has been implicated in promoting atherosclerosis in patients infected with HIV. We evaluated whether CCL2 gene variants are associated with metabolic disturbances and plasma CCL2 levels in HIV-infected patients. METHODS AND RESULTS: CCL2 genotypes and estimated haplotypes, plasma CCL2 levels and indicators of metabolic status in HIV-infected patients were compared with a...
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