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Article

Association study of a functional Toll-like receptor 4 polymorphism with susceptibility to gastric mucosa-associated lymphoid tissue lymphoma.

Leukemia & lymphoma - 1 Jun 2005

Hellmig Stephan, Fischbach Wolfgang, Goebeler-Kolve Maria-Elisabeth, Fölsch Ulrich Robert, Hampe Jochen, Schreiber Stefan

Abstract excerpt

Toll-like receptor 4, as part of innate immune response, is the main receptor for lipopolysaccharide on marginal zone B cells. The rare allele of TLR4 Asp299Gly attenuates receptor signaling and diminishes the inflammatory response. We genotyped 87 patients with gastric mucosa-associated lymphoid tissue (MALT) lymphoma, 594 Helicobacter pylori positive controls and 358 healthy blood donors to investigate an...

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Share to Gastric Mucosa
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphoma, B-Cell, Marginal Zone

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Source

Identifiers

PMID: 16019531
DOI: 10.1080/1042819050086451

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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